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Science + Longevity

Barbell Medicine

Strength training + health, evidence-forward

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Personal Fat Threshold Theory Explained

The personal fat threshold theory says obesity begins when a person's fat cells run out of storage room, not at any fixed weight or BMI. Once storage fills up, fatty acids leak into the liver, muscle, and pancreas, causing insulin resistance. Removing fat surgically does not reverse this; restoring storage capacity does.

August 20, 2026 · 8 min read

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Who Needs Testosterone Replacement Therapy?

Barbell Medicine physicians Jordan Feigenbaum and Austin Baraki say testosterone therapy in the US is both overprescribed and underprescribed. They point to a 45-man Sydney trial where raising testosterone from 310 to 510 ng/dL did not beat placebo, and to the Traverse trial's reassuring two-year heart-safety data.

August 27, 2026 · 8 min read

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