Nubank founder David Vélez argues global banking is still in the Blockbuster era, with incumbents holding 90% of a $10 trillion industry (02:38), while Nubank's own AI foundation model and a flattened org structure let it serve 140 million customers at 3% of a traditional bank's cost (05:32).
Stanford neuroscientist Andrew Huberman lays out a three-step method for falling asleep fast, predicts that Meta, OpenAI, and Anthropic will become biotech companies racing to read and write the nervous system, and describes a memory experiment that undercuts how neuroscience thought memory worked. He also discusses the scientist who CRISPR-edited twin babies and reportedly now works in Austin, Texas.
Gabe Stengel, CEO of AI finance platform Rogo, says AI will force top investors to rebuild their firms within five years. He argues vertical AI wins by building the compliance and workflow plumbing banks need, not just smarter models, and predicts pricing will shift from per-seat fees toward per-outcome charges for deals and reports.
Michael Moritz says imprints formed before age fourteen shape a person's drive for life. The former Sequoia Capital leader traces this idea to his refugee family's escape from Nazi Germany, then applies it to founders, Manchester United manager Alex Ferguson's leadership, and the vanishing information edge that once defined early venture capital.
Historian Walter Russell Mead argues American state power is thriving even as the postwar world order it built is collapsing. He traces a 300-year maritime playbook from the Dutch Republic through Britain to the US, then applies it to Trump, drones in Ukraine, India's rise, and AI-driven deterrence.
Sarah Guo, founder of Conviction, says AI's future rides on about 250 frontier researchers, not compute budgets alone. She traces the real bottleneck to energy and regulation rather than algorithms, describes backing robotics startup Sunday Robotics after one meeting, and argues Jevons paradox means AI will make people work more, not less.
